Published Papers


Skip Navigation


UOU Logo

Top Menu

Total Search


Home > Research > Research Outcome >Published Papers

Document Contents

Published Papers

Search :

Search

Factors associated with successful response to neurolytic celiac plexus block in patients with upper abdominal cancer-related pain: a retrospective study

Abstract
Background: Prior studies have reported that 40%-90% of the patients with celiac plexus-mediated visceral pain benefit from the neurolytic celiac plexus block (NCPB), but the predictive factors of response to NCPB have not been evaluated extensively. This study aimed to identify the factors associated with the immediate analgesic effectiveness of NCPB in patients with intractable upper abdominal cancer-related pain. Methods: A retrospective review was performed of 513 patients who underwent NCPB for upper abdominal cancer-related pain. Response to the procedure was de- fined as (1) a decrease of ≥ 50% or ≥ 4 points on the numerical rating scale (NRS) in pain intensity from the baseline without an increase in opioid requirement, or (2) a decrease of ≥ 30% or ≥ 2 points on the NRS from the baseline with simultane- ously reduced opioid consumption after NCPB. Logistic regression analysis was per- formed to determine the factors associated with successful responses to NCPB. Results: Among the 513 patients included in the analysis, 255 (49.8%) and 258 (50.2%) patients were in the non-responder and responder group after NCPB, re- spectively. Multivariable logistic regression analysis showed that diabetes (odds ratio [OR] = 0.644, P = 0.035), history of upper abdominal surgery (OR = 0.691, P = 0.040), and celiac metastasis (OR = 1.496, P = 0.039) were the independent fac- tors associated with response to NCPB. Conclusions: Celiac plexus metastases, absence of diabetes, and absence of prior upper abdominal surgery may be independently associated with better response to NCPB for upper abdominal cancer-related pain.

The administrative responsibility of the content.

By cliking the email below, you can send an e-mail to the person in charge.

Last Modified : Apr 9, 2013
  • Office : UOU International
  • Phone : +82-52-220-5957
  • Staff in Charge : Sean Park

Contents Review

Review the content back to the main content of the current page provides links to allow access.


Contact menu

CONNECT WITH UOU

Address

93 Daehak-ro, Nam-gu,
Ulsan (44610), Korea

Tel

Phone: +82-52-220-5952(~5959)

Fax

Fax: +82-52-224-2061

Email

QUICK LINK

Sitemap menu

CONTENTS

Join us and keep up-to-date on what is happenting around University of Ulsan.

Sitemap


Footer menu

CopyRight

Copyright 2012 University of Ulsan, All Rights Reserved.


Review Navigation